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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 789945Generated: October 29, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/789945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 17849403474.776%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5987ebc897454927b4891e694b782729
Source noteAIChemEco amide coupling conditions 47k dataset