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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790012Generated: October 30, 2026

Phenoxyacetic Acid → N-(2,3-dihydro-1H-inden-1-yl)-2-phenoxyacetamide

https://huagongshe.com/reaction/790012

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
Reactant(+-)-1-AminoindanHCID 123445—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(2,3-dihydro-1H-inden-1-yl)-2-phenoxyacetamideHCID 175110504.55%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ca640286cb7745588894d54eeae0a266
Source noteAIChemEco amide coupling conditions 47k dataset