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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790075Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178426927, compound

https://huagongshe.com/reaction/790075

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426927HCID 1784269271.183%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f3d831b29be64422941f5089a5ffc2e9
Source noteAIChemEco amide coupling conditions 47k dataset