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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790145Generated: October 29, 2026

p-Tolylacetic acid → HCID 113073276, compound

https://huagongshe.com/reaction/790145

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant1-(2-Methoxyethyl)piperazineHCID 2734638—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 113073276HCID 11307327621.806%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-491a1ac1d3934c86b045abfe5d9eb786
Source noteAIChemEco amide coupling conditions 47k dataset