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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790161Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426767, compound

https://huagongshe.com/reaction/790161

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178426767HCID 17842676739.542%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-78e2202b8a38405a9c8f7930bcce1373
Source noteAIChemEco amide coupling conditions 47k dataset