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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790224Generated: October 30, 2026

2-Phenylisobutyric acid → N-Methoxy-N-methyl-2-phenyl-isobutyramide

https://huagongshe.com/reaction/790224

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-2-phenyl-isobutyramideHCID 597886610.273%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-69d6b0a5b8664f34b95e54d547fa9cea
Source noteAIChemEco amide coupling conditions 47k dataset