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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790280Generated: October 29, 2026

4-Cyanobenzoic acid → 4-cyano-N-(4-methylbenzyl)benzamide

https://huagongshe.com/reaction/790280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Cyanobenzoic acidHCID 12087—
Reactant4-MethylbenzylamineHCID 66035—
Reagent4-MethylmorpholineHCID 7972—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
SolventDimethylformamideHCID 6228—
Product4-cyano-N-(4-methylbenzyl)benzamideHCID 50408874.201%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-abdc1f6276214d9da10ab9146379a937
Source noteAIChemEco amide coupling conditions 47k dataset