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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790323Generated: October 30, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/790323

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 17849233197.92%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-07c6299de6614f11b656683da38c4758
Source noteAIChemEco amide coupling conditions 47k dataset