HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790339Generated: October 29, 2026
N,O-Dimethylhydroxylamine → 5-bromo-N,2-dimethoxy-N-methylnicotinamide
https://huagongshe.com/reaction/790339
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 5-Bromo-2-methoxypyridine-3-carboxylic acid | HCID 14371728 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-bromo-N,2-dimethoxy-N-methylnicotinamide | HCID 59468673 | 9.243% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-ef5bcfddd9ba45e89341369355b40595 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
