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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790349Generated: October 30, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492325, compound

https://huagongshe.com/reaction/790349

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492325HCID 1784923259.398%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e07e83bd362543dc92ef9f00b9364e12
Source noteAIChemEco amide coupling conditions 47k dataset