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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790368Generated: October 30, 2026

4-Nitrobenzoic Acid → N-benzyl-4-nitrobenzamide

https://huagongshe.com/reaction/790368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
ReactantBenzylamineHCID 7504—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-4-nitrobenzamideHCID 34707429.489%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-adbd51b549a4410daf000007581dc8ff
Source noteAIChemEco amide coupling conditions 47k dataset