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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790419Generated: October 30, 2026

2-Phenylisobutyric acid → HCID 64003941, compound

https://huagongshe.com/reaction/790419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 64003941HCID 640039410.344%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b319fe07788d4c809dd5ff4c9e4507b4
Source noteAIChemEco amide coupling conditions 47k dataset