(2-Dimethoxymethyl-3-fluoro-5-methoxy-6-nitro-phenyl)-(2-fluoro-4-iodo-phenyl)-amine → HCID 86656240, compound

Participants

Reaction Steps

A mixture of (2-dimethoxymethyl-3-fluoro-5-methoxy-6-nitro-phenyl)-(2-fluoro-4-iodo-phenyl)-amine (4.2 g, 8.7 mmol) in diethyl ether (70 mL) and 4M HCl (50 mL) was stirred at room temperature for 8 hours. The mixture was extracted with ethyl acetate, the organic extract washed with water, dried (Na2SO4), filtered and concentrated in vacuo to give the title compound as a yellow solid (3.1 g, 82%). LCMS (Method B) RT=4.00 no molecular ion.

Provenance & Evidence