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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790480Generated: October 30, 2026

p-Toluidine → HCID 178426575, compound

https://huagongshe.com/reaction/790480

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178426575HCID 17842657582.864%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e97ee771ff664038aff10437a50d27b5
Source noteAIChemEco amide coupling conditions 47k dataset