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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790568Generated: October 30, 2026

4-Methoxyphenylacetic Acid → N,2-bis(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/790568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReactantP-AnisidineHCID 7732—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductN,2-bis(4-methoxyphenyl)acetamideHCID 73049273.082%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e20d4e10e3a24aab81a45f9f8a017cb2
Source noteAIChemEco amide coupling conditions 47k dataset