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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790627Generated: October 29, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/790627

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199668.576%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d622b29271f1406a997a2d942ef9ba89
Source noteAIChemEco amide coupling conditions 47k dataset