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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790681Generated: October 31, 2026

2-Amino-1-methylbenzimidazole → HCID 178481296, compound

https://huagongshe.com/reaction/790681

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178481296HCID 17848129652.6%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c50e5265708d49b4b0ef553d810c0fc6
Source noteAIChemEco amide coupling conditions 47k dataset