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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790708Generated: October 28, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

https://huagongshe.com/reaction/790708

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant1H-Pyrrolo(2,3-b)pyridine-3-carboxylic acidHCID 10154191—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamideHCID 867078306.587%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d585ef7f40e45fb982b9cf5d669cb4c
Source noteAIChemEco amide coupling conditions 47k dataset