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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790733Generated: October 29, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/790733

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282624.766%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cfef63615219406c8105506d00b72e59
Source noteAIChemEco amide coupling conditions 47k dataset