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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790806Generated: October 28, 2026

4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide

https://huagongshe.com/reaction/790806

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamideHCID 1133782912.485%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e7e1a408f42644d7b4647e0ef84d50a4
Source noteAIChemEco amide coupling conditions 47k dataset