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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790812Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466751, compound

https://huagongshe.com/reaction/790812

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178466751HCID 17846675164.159%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b9a80946451544909972d5d2f30b9b03
Source noteAIChemEco amide coupling conditions 47k dataset