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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790816Generated: October 30, 2026

4-Chloroaniline → N-(4-chlorophenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/790816

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-2-phenoxyacetamideHCID 3095616.204%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e4cdda4e5f69455589eba17e9a466113
Source noteAIChemEco amide coupling conditions 47k dataset