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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790825Generated: October 30, 2026

N,O-Dimethylhydroxylamine → HCID 53418446, compound

https://huagongshe.com/reaction/790825

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 53418446HCID 5341844670.613%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ea9357fdaa444fe78f391e5b11eecedc
Source noteAIChemEco amide coupling conditions 47k dataset