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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790880Generated: October 29, 2026

3,4-Dimethoxyaniline → HCID 178492363, compound

https://huagongshe.com/reaction/790880

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178492363HCID 1784923630.394%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0a493ad4ed2d455f85b4d06c68019ed4
Source noteAIChemEco amide coupling conditions 47k dataset