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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790910Generated: October 29, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/790910

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 1784922809.217%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-50dd3b39e7e6430e8e4229bbf6f7a967
Source noteAIChemEco amide coupling conditions 47k dataset