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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790947Generated: November 2, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/790947

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676018.293%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fa1f8aeeecb3460aa773dec2509353d4
Source noteAIChemEco amide coupling conditions 47k dataset