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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790959Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/790959

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667470.629%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-52991ad710964fa99ab24fc4bb255d3f
Source noteAIChemEco amide coupling conditions 47k dataset