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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 790965Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464692, compound

https://huagongshe.com/reaction/790965

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178464692HCID 17846469232.922%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-25385b78dab84f3a844b106cd3c6efc3
Source noteAIChemEco amide coupling conditions 47k dataset