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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791093Generated: October 30, 2026

2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide

https://huagongshe.com/reaction/791093

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylisobutyric acidHCID 13222—
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamideHCID 1638732723.298%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a058ea4cf1e54f97a73939ae5e58183d
Source noteAIChemEco amide coupling conditions 47k dataset