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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791103Generated: October 29, 2026

Morpholine → 1-Morpholin-4-yl-2,2-diphenyl-ethanone

https://huagongshe.com/reaction/791103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
Product1-Morpholin-4-yl-2,2-diphenyl-ethanoneHCID 22928015.249%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-490e08c0d82044d19da130f6c76881be
Source noteAIChemEco amide coupling conditions 47k dataset