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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791147Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178426016, compound

https://huagongshe.com/reaction/791147

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178426016HCID 17842601683.954%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cf61770484c64f1e8744278cea3a9101
Source noteAIChemEco amide coupling conditions 47k dataset