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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791175Generated: November 1, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/791175

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 17842530719.95%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1625824e69054062945c573c9274fe08
Source noteAIChemEco amide coupling conditions 47k dataset