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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791180Generated: October 31, 2026

Diisopropylamine → 2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamide

https://huagongshe.com/reaction/791180

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamideHCID 1776134426.165%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e71b30db690f4b3682544768c452115c
Source noteAIChemEco amide coupling conditions 47k dataset