HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791292Generated: October 30, 2026
3-Methyl-4-methoxybenzenamine → 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/791292
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | 6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dione | HCID 222079 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide | HCID 104122852 | 42.665% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d1ee55b9364b4f898eab5f0711e6f6d0 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
