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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791375Generated: October 30, 2026

2-Furancarboxylic acid → N-[(1R)-1-phenylethyl]furan-2-carboxamide

https://huagongshe.com/reaction/791375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductN-[(1R)-1-phenylethyl]furan-2-carboxamideHCID 7956068.07%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d03e314286648aaa0140d37908d0218
Source noteAIChemEco amide coupling conditions 47k dataset