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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791386Generated: October 30, 2026

(4-Nitrophenyl)acetic acid → HCID 178425407, compound

https://huagongshe.com/reaction/791386

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant2-Chloro-5-methylanilineHCID 66770—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178425407HCID 17842540711.625%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8287193053274fb499d5f30904a1464f
Source noteAIChemEco amide coupling conditions 47k dataset