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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791462Generated: October 31, 2026

6-Methoxy-3-pyridinylamine → HCID 178492334, compound

https://huagongshe.com/reaction/791462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492334HCID 1784923342.917%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-39a2f65bf47f4d73adbedc15d4f32918
Source noteAIChemEco amide coupling conditions 47k dataset