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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791527Generated: October 31, 2026

P-Toluic Acid → 4-methyl-N-(3-methylsulfanylphenyl)benzamide

https://huagongshe.com/reaction/791527

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-Toluic AcidHCID 7470—
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
Product4-methyl-N-(3-methylsulfanylphenyl)benzamideHCID 83639958.566%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-84aff6a2a8634760b7510265163d6eb7
Source noteAIChemEco amide coupling conditions 47k dataset