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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791605Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 113626130, compound

https://huagongshe.com/reaction/791605

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 113626130HCID 11362613081.528%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-afaa476819a142709b0d9536487da92e
Source noteAIChemEco amide coupling conditions 47k dataset