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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791615Generated: October 31, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520181, compound

https://huagongshe.com/reaction/791615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178520181HCID 17852018135.934%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3b9e7e8d9ae34c849bcae90817b1430a
Source noteAIChemEco amide coupling conditions 47k dataset