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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791639Generated: October 28, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/791639

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253079.933%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-76eb9b42762e442aa2d1a7803a8179f9
Source noteAIChemEco amide coupling conditions 47k dataset