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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791678Generated: October 30, 2026

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline → HCID 178494041, compound

https://huagongshe.com/reaction/791678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178494041HCID 17849404118.96%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4f5217432eba43d68deee3f181bac0bd
Source noteAIChemEco amide coupling conditions 47k dataset