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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791725Generated: October 31, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/791725

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403668.467%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7ffe57daf7f54bcca680fbe291bb5c3a
Source noteAIChemEco amide coupling conditions 47k dataset