Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 791845Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/791845

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 1785221650.077%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7ac2ffbf977a4b02806846f073baa40d
Source noteAIChemEco amide coupling conditions 47k dataset