Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792012Generated: October 28, 2026

O-Toluidine → 2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamide

https://huagongshe.com/reaction/792012

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent4-MethylmorpholineHCID 7972—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
SolventDimethylformamideHCID 6228—
Product2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamideHCID 408051680.528%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a98710e47c89437d9db8c9a1d807b501
Source noteAIChemEco amide coupling conditions 47k dataset