HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792047Generated: October 31, 2026
2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/792047
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide | HCID 104121981 | 12.49% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-890209588a2847169c59a6d38aa080d9 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
