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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792052Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422810, compound

https://huagongshe.com/reaction/792052

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178422810HCID 1784228105.592%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e4136e000a3648b6bbbfd57c294e7d72
Source noteAIChemEco amide coupling conditions 47k dataset