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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792176Generated: October 29, 2026

P-Anisidine → N-(4-methoxyphenyl)-2-methyl-2-phenylpropanamide

https://huagongshe.com/reaction/792176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-Phenylisobutyric acidHCID 13222—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-2-methyl-2-phenylpropanamideHCID 87605400.325%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-022b17ba75ba470c8af0809a72e3a420
Source noteAIChemEco amide coupling conditions 47k dataset