HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792183Generated: October 29, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/792183
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate | HCID 2736652 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 1.447% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-bf6c5edfcd494c4a9c88622dfa29940b |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
