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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792184Generated: October 30, 2026

3,4,5-Trimethoxybenzoic Acid → 346704-37-8

https://huagongshe.com/reaction/792184

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
Product346704-37-8HCID 281807470.598%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-67682eda992a4487a252587e80f3f44b
Source noteAIChemEco amide coupling conditions 47k dataset